DDI, smartphone, Data Matrix, anticoagulant

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DDI, smartphone, Data Matrix, anticoagulant

Post by jerome » 26 July 2014, 06:03

A Data Matrix code is printed on every drugs boxes, at least in France. Apps have been released on smartphones to scan them and get information about the drug.

medicaments.gouv https://play.google.com/store/apps/deta ... s&hl=fr_FR

A free app from the french minister of Health, ANSM (drug agency) & HAS (gov scientific committee giving recommendations) that gives information about drugs. No DDIs.

Scan Pharma (by database editor BCB Dexther) is meant to check the home pharmacy, including drug expiration dates. The free version only gives name of drug and expiration date. For complete information, user has to buy the full version of the app. No DDIs.

Another scanning app based on ANSM french public drugs list by a french developer: http://sebz00.free.fr/

It could be interesting to adapt a basic version of FreeDiams with drug drug interactions for smartphones.

The prototype could be used for long term VKA patients. Before taking any new drug, a patient on VKA should ask his doctor or pharmacist if the drug is safe for his condition and current medication. As a double check or if medical advice is not readily available, he could scan the box and get important information and warning.

That could help prevent life threatening or serious drug adverse events such as this one:

Acute warfarin toxicity: An unanticipated consequence of amoxicillin/clavulanate administration
http://www.ncbi.nlm.nih.gov/pmc/article ... po=30.0000

This case involved a prescription of amoxcillin clavulanic acid by a health care professional (dentist) who didn't ask about the patient's current medication (warfarin) or past condition (protein C deficiency, pulmonary embolism), which could have triggered an alarm... The patient ended up in the ER with gum bleeding following dental extraction, forearm hematoma, hematuria, INR =20,4. He was given blood product (fresh frozen plasma) and vitamin K.

If you consider the swiss cheese adverse event model, a mobile app interaction checker could be another layer preventing the alignment of holes leading to adverse events.

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